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A software implementation for recovering the individual retinal pigment epithelial (RPE) cells from single noisy adaptive optics optical coherence tomography (AOOCT) images. This software was primarily developed by Vineeta Das and Johnny Tam, with research support from Intramural Research Program of the National Institutes of Health, National Eye Institute. Additional details about the algorithms used can be found in the reference listed below.

Public Access

A software package for segmenting the boundaries of cone photoreceptors in non-confocal adaptive optics images such as split detection. This software was primarily developed by Jianfei Liu, Andrei Volkov, and Johnny Tam, with research support from the Intramural Research Program of the National Institutes of Health, National Eye Institute. Additional details about the algorithms used can be found in the reference listed below.

Public Access

Look up gene expression by retina cell type across loads of different studies, four organisms, and multiple developmental stages.

Public Access

A database of 20,000 photographs, selected by human observers from over 200,000 photographs as those that contain a salient object.

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Explore Our Research Areas

AMD Integrative Biology Initiative

Learn about the precise description of AMD disease pathobiology by using AMD genetic risk factors as sentinels for specific RPE signaling pathways and for changes in RPE physiology.

Adaptive Optics

Explore open-source software tools developed for adaptive optics retinal imaging data.

eyeIntegration

Probe the relatedness and biological processes between the cornea, retina, RPE (choroid), and the rest of the human tissues by using a fully integrated dataset with differential expression, clustering, and GO term enrichment tools.

eyeGENE® (National Ophthalmic Disease Genotyping and Phenotyping Network)

Learn about the phenotype and genotype data for over 30 inherited eye conditions.

Next Generation Sequencing (Ocular Genomes)

Learn more about data and code generated from the Neurobiology Neurodegeneration and Repair Laboratory at NEI.

Ocular Proteome

NEI has made the Ocular Proteome dataset available so that researchers can analyze protein changes related to genetic eye diseases.

Patient-Reported Outcomes with LASIK (PROWL)

Learn about a clinical trial aimed to validate a survey tool that assesses visual symptoms both before and after LASIK surgery and to identify changes over a short period of time.