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  • Learn about the precise description of AMD disease pathobiology by using AMD genetic risk factors as sentinels for specific RPE signaling pathways and for changes in RPE physiology.

  • Probe the relatedness and biological processes between the cornea, retina, RPE (choroid), and the rest of the human tissues by using a fully integrated dataset with differential expression, clustering, and GO term enrichment tools.

  • NEI has made the Ocular Proteome dataset available so that researchers can analyze protein changes related to genetic eye diseases. The dataset holds structures for over 100 proteins and over 1 million variants, cataloging the proteins atomic structures and stability generated by global computational mutagenesis.